Angelman Syndrome (or AS) is a neurodevelopmental disorder affecting approximately 1 in 15,000 live births.
Although the cause of AS is known, there are currently no treatments available for this disorder. FAST is
committed to funding the research that will lead to treatments and eventually a cure. Learn about Angelman
Syndrome and why we believe a cure is within reach...
Why There is Hope for a Cure
Because we know the cause of AS is a loss of functional levels of UBE3A in
the brain we already possess the basic knowledge we need to start the search
for a viable treatment.
FAST Faqs: Genetics 101
Angelman Syndrome (or AS) is caused by the lack of function of one specific gene, called UBE3A.
To understand this, we first need to understand how chromosomes and genes work together to
allow our brains to function.
FAST Faqs: Variability
When a parent is told the diagnosis is Angelman syndrome and they are made familiar
with the characteristics of this disorder, such as seizures, sleep problems, non-verbal
communication, severe cognitive impairment and more, it is quite natural to wonder what
the future may hold.